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Requisites
Measures

Number of red blood cells in the blood

Identifies

Red blood cell disorders

Measures: Number of red blood cells in the blood

Identifies: Red blood cell disorders

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What is the maximum days the report can be obtained for the test

The maximum days the report can be obtained for the test UGT1A1 Gene Analysis Test is 7 days.

What are the prerequisites for the test UGT1A1 Gene Analysis Test

  • Patients must be at least 18 years old
  • Patients must have a prescription from a healthcare provider
  • Patients must have fasted for at least 8 hours prior to the test
  • Patients must not have taken any medications that may interfere with the test results

What are the measure values for the test UGT1A1 Gene Analysis Test

  • Normal Range: 6 - 12 U/g Hb
  • Intermediate Range: 13 - 29 U/g Hb
  • High Range: ≥30 U/g Hb

What does this test UGT1A1 Gene Analysis Test identify?

  • This test identifies variations in the UGT1A1 gene, which is responsible for encoding an enzyme called UDP-glucuronosyltransferase 1A1.
  • UGT1A1 enzyme plays a crucial role in the metabolism of bilirubin, a waste product of red blood cell breakdown.
  • Variations in the UGT1A1 gene can lead to conditions such as Gilbert syndrome, Crigler-Najjar syndrome, and increased risk of hyperbilirubinemia.
  • By analyzing the UGT1A1 gene, this test can help identify individuals at risk for these conditions and guide treatment decisions.

Why is this test UGT1A1 Gene Analysis Test taken?

The UGT1A1 Gene Analysis Test is taken to determine the genetic variations in the UGT1A1 gene. This gene encodes an enzyme called UDP-glucuronosyltransferase 1A1, which is responsible for the process of glucuronidation - a phase II metabolism pathway that helps in the detoxification and elimination of various substances from the body.

Genetic variations in the UGT1A1 gene can affect the activity of the enzyme, leading to differences in how certain drugs, toxins, and other substances are processed and eliminated. This can have implications for drug dosing, toxicity, and treatment outcomes.

Individuals may be recommended to undergo the UGT1A1 Gene Analysis Test for various reasons, such as prior to starting certain medications that are metabolized by UGT1A1, to assess the risk of adverse drug reactions, or to guide personalized treatment plans.

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